منابع مشابه
Ovarian Hyperstimulation Caused by Gonadotroph Pituitary Adenoma--Review.
Ovarian hyperstimulation syndrome (OHSS) occurs mostly as an iatrogenic complication of assisted reproductive technology. Gonadotroph pituitary adenomas are rarely associated with OHSS. To the authors' knowledge, to date only 30 cases of spontaneous ovarian stimulation associated with gonadotroph adenomas have been reported in women and only 2 in children. The most common symptoms in such cases...
متن کاملLineage-Specific Restraint of Pituitary Gonadotroph Cell Adenoma Growth
Although pituitary adenomas are usually benign, unique trophic mechanisms restraining cell proliferation are unclear. As GH-secreting adenomas are associated with p53/p21-dependent senescence, we tested mechanisms constraining non-functioning pituitary adenoma growth. Thirty six gonadotroph-derived non-functioning pituitary adenomas all exhibited DNA damage, but undetectable p21 expression. How...
متن کاملFunctioning oxyphil parathyroid adenoma.
A hormonally active oxyphil adenoma of the parathyroid masqueraded as a thyroid nodule and was present as a palpable neck mass for more than six years prior to the onset of clinically obvious hyperparathyroidism. The slow evolution of the hyperparathyroidism in the presence of a relatively large adenoma was correlated with the presumptive low hormonal synthetic capacity of oxyphil cells that fo...
متن کاملFunctioning Pituitary Adenoma
Mahdi Sharif-Alhoseini1, Edward R. Laws2 and Vafa Rahimi-Movaghar3,4 1Sina Trauma and Surgery Research Center, Tehran University of Medical Sciences, Tehran, 2Department of Neurosurgery, Brigham & Women's Hospital, Harvard Medical School, Boston, Massachusetts, 3Sina Trauma and Surgery Research Center, Department of Neurosurgery, Tehran University of Medical Sciences, Tehran, 4Research Centre f...
متن کاملEffect of temozolomide on cell viability in gonadotroph adenoma cell lines.
Invasive pituitary adenomas are usually refractory to routine neurosurgery, radiosurgery or medications, and alternative therapies are needed. The effects of temozolomide (TMZ) on the inhibition of gonadotroph adenoma cell viability and hormone secretion were evaluated. Cell viability and IC50 values were evaluated after αT3-1 cells were treated with TMZ (31.25-1000 µM) or vehicle for 0-72 h. C...
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ژورنال
عنوان ژورنال: Chinese Medical Journal
سال: 2019
ISSN: 0366-6999
DOI: 10.1097/cm9.0000000000000184